In recent years, the term 'growth hormone' has been most commonly associated with athletes and with various doping scams. Due to its misuse, this ingredient had ill repute for a while. On the other hand, it’s quite efficient conventional therapy for insulin deficiency, which causes growth problems in kids.
The hypophysis is in charge of the secretion of the growth hormone (HGH). It has a vital role in cell regeneration, increase, and development of healthy human tissue, including the brain and other vital organs. The effect of this hormone is most noticeable during puberty when the growth and development of the body are most progressive.
After entering the bloodstream, HGH stays there for a while. That's enough time for the liver to convert it to growth factors, such as insulin. This factor has the properties of promoting growth in every cell in the body.
As explained on https://anabolicsteroiddrugs.com/mecasermin/, mecasermin is a synthetic form of insulin-like growth factor and is quite essential for bone and muscle development when the body can't produce insulin independently.
On-Label Use of Mecasermin
Synthetic growth hormone, developed about four decades ago, has been approved by the FDA for specific applications in adults and children. It is a traditional therapy for people who have a lower insulin level than needed. But when the levels of these hormones in the body are regular, it's marked as off-label use.
The medicine Increlex contains mecasermin as an active substance, which is a copy of insulin. It alters the missing hormone and stimulates cells to divide and grow and to absorb nutrients, supporting the growth of body tissue. Adequate therapy with this medication has the effect of increasing the growth rate of children whose height progress is delayed.
The use of growth factors, such as insulin, is known to stimulate bone metabolism. It is crucial in people who have experienced any injury or fracture, and there are problems with bone healing and mineralization. The use of Mecasermin therapy accelerates bone regeneration, and the best results are achieved by topical application (by injection).
Off-Label Use in Athletes
Numerous athletes started to take Increlex when it was discovered that growth hormone improves a physical capacity through stimulation of collagen synthesis in skeletal muscle and tendons. It increases muscle strength and improves physical performance. Balancing insulin levels in the body speeds up metabolism and encourages it to promote tissue growth.
There are indications that mecasermin can be used as a weight-loss preparation. Physically active people and professional athletes use Increlex as a fat burner. It has been proven that synthetic growth hormone accelerates lipolysis, that is, the melting of internal fat deposits and their conversion into energy.
However, this is not the original purpose of the drug, as it's labeled exclusively as a pediatric drug. People who want to get Increlex over-the-counter should be cautious and buy only from proven suppliers of sports supplements. More on OTC drugs read on this source.
Safety of Use
Increlex is officially approved for the treatment of specific conditions. But, due to the frequency of side effects, it is mandatory to carry out therapy under constant medical supervision. This treatment is only suitable for kids who are still in their growth stage. After the end of puberty, mecasermin therapy won't bring results.
Most side effects of this medicine are associated with an allergic reaction to one of the components of the drug. Patients can experience rashes, swelling, and fewer. However, in certain situations, there are risks of more severe complications, such as enlargement of the tonsils or swelling of the salivary glands.
It is essential to know how to administer the medicine - mecasermin goes directly under the skin and not into the vein. When giving Increlex therapy, make sure patients take medicine right before or after the meal. Otherwise, blood sugar, low blood pressure, nausea, and fainting may occur. Pay attention if the patients complain of pain in the sinus area.
Some medicines have many benefits, but there are good reasons why they have not been formally approved for use. Benefits of Increlex in treating insulin deficiency take an advantage over the frequency of its side effects. But buying an over-the-counter medication, using it as supplementation, and conducting therapy without medical supervision carry some risks.