The mental distress is intertwined with physical health, especially the metabolic, according to data collected on more than 10 thousand people, the weight and the amount of insulin circulating in the blood during childhood and adolescence may contribute to increase the probability of meeting, as adults, to disorders such as depression and psychosis.
The data, published in the journal JAMA Psychiatry, derived from analysis of the database of the Avon Longitudinal Study of Parents and Children, a study that involved about 15 thousand people in the west of England: the children of the families of the participants were followed from one to 24 years and during all of this period were collected at regular intervals numerous health data, including levels of insulin in the blood (of over 5 thousand participants) and weight (over 10 thousand). The hormone, which is required for utilization of glucose by the tissues, is crucial for a good balance of energy metabolism; the researchers observed that 75 percent maintained in accordance with the levels of insulin throughout childhood and adolescence, 3% li has always had high, 15 to 18 percent has seen them increase gradually. "The group in which the insulin has been consistently high over the years he has recorded a higher chance of developing psychosis in adulthood," explains the coordinator of the investigation, Benjamin Perry of the Department of psychiatry at the university of Cambridge. Evaluating the effect of the weight, we verified that an overweight since childhood, does not affect the risk of depression as adults, instead of grease during puberty yes, especially in girls: it is possible that some of the factors that facilitate the increase of the weight a horse of this delicate period are risk factors that are equally critical to the subsequent development of depression."
Some evidence of a susceptibility to mental ill health might, therefore, be present long before the development of symptoms of the psychiatric disorder. This means that by measuring the insulin in the blood in children and young people you will be able to intercept those from the adult will be at the risk of psychosis, or that monitor the balance in the teenagers say who could then get sick of depression? "Hyperinsulinemia and weight gain at puberty are the two risk factors, among many others, genetic and environmental: these two measures can predict the likelihood of future psychiatric illness — specific Perry —. If anything, the data indicate that not always the mental pathology appears first: we know that psychosis and depression are often associated with diabetes and obesity, but it is always assumed that these were the result of a life-style misuse of the patients. However, it is possible that it is not always so, and that, in some, however, health problems already identified in childhood are risk factors for the subsequent development of mental disorders". Of the rest, several data suggest that hyperinsulinemia and subsequent insulin resistance has a role in the increased risk of cognitive disorders in people with diabetes: a proper metabolism of glucose in short, is no stranger to the good functionality of the brain, and the new study underlines once again how interconnected the physical and the mental. So, concludes Perry, "in young adults with mental disorders, it is appropriate to assess the status of physical health, in those with organic disorders, monitor the mental well being".